Hello Reader,

Lots going on at the studio right now, so let’s dive straight in:​
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1. New animation

We’ve just wrapped up an exciting 3D animation for Satellos, and the full video will be released soon.

After watching the final version, our client felt the voice-over wasn’t quite right - something that only really becomes clear once you see and hear everything together. Luckily, changing voice-over is no big deal. There are plenty of talented artists who can bring just the right emotion to a piece.

Of course, they're all feeling the pressure from AI right now. I’m curious myself about how well AI can perform in this space. So far, we haven’t used synthetic voices in any of our projects. But who knows - never say never.

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2. Behind the scenes

2.1 No Patient Left Behind - our longest project yet

This has been the longest animation in our 13-year history — over a year in the making, and now finally nearing completion.

The concept compares the development of a new drug to climbing a mountain. We’d previously created a shorter version of this video, and now we’ve expanded it to explain the entire journey in much greater detail.

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2.2 Breaking down complex science

Here’s a sneak peek from our new animation for Crucible Therapeutics.

The top image shows Crucible’s original scientific illustration explaining the mechanism behind ALS — a devastating neurodegenerative disease. Below is a screenshot from our animation.

Our job? To strip the science down to its essentials and tell a compelling, accurate story:

• In ALS, rogue nuclear RNAs escape into the cytoplasm, where they trigger the formation of toxic proteins and damage neural cells.
• Crucible Therapeutics has identified a key player in this process: a protein called SRSF1.
• By depleting SRSF1, the transport of rogue RNA is blocked — helping to preserve essential cell functions.

This kind of work is what we love: turning complexity into clarity.

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3. From the mountains

We spent a long weekend in the Polish mountains, in an old spa town called Krynica-Zdrój. The town center was packed with tourists, but the mountains? Beautiful and almost completely empty.

While Emilia was happy to stay by the pool, I took the chance to explore on two wheels. Next time, I’ll definitely bring a proper mountain bike - the trails were far too rocky for my current setup.

Oh, and I may have fallen in love with a bonsai tree. Still thinking about it.

Talk soon,
Frank

P.S.
If you’re planning an animation in the next few months, just get in touch. I’m always happy to bounce around some initial ideas. Book a meeting with me here.

Frank Metzel - CEO Life-Science-Animation.com​
Follow me on LinkedIn​
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